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IGF-1 LR3

$99.99

Research Use Only

This product is intended for laboratory research use only. Not for human consumption or clinical use.

Overview

GF-1 LR3 is a research peptide analog of human insulin-like growth factor 1 (IGF-1) containing a 13–amino acid N-terminal extension that enhances stability and receptor binding. It interacts with the IGF-1 receptor to activate PI3K/Akt and MAPK/ERK pathways involved in cellular growth, differentiation, and metabolic regulation. IGF-1 LR3 is used in experimental models to study peptide-mediated anabolic signaling, receptor kinetics, and tissue remodeling mechanisms.

IGF1-LR3 (insulin-like growth factor-1 long arginine-3) is a synthetic analog of insulin-like growth factor-1 engineered for use in laboratory research. Structural modifications include N-terminal amino acid extension and substitution of glutamic acid with arginine at position three, resulting in reduced affinity for IGF-binding proteins. These modifications extend molecular persistence in experimental systems, enabling prolonged interaction with IGF-associated receptors in controlled in-vitro and in-vivo animal models. Preclinical research utilizes IGF1-LR3 as a tool compound to investigate growth factor-mediated signaling, cellular proliferation pathways, differentiation programs, and metabolic signaling cascades. All discussion herein is limited to experimental research contexts and does not imply applied, therapeutic, or physiological use.

Storage & Handling

Lyophilized Powder
Store at 2-8°C. Protect from light and moisture.
Reconstituted Solution
Store at 2-8°C for longer usage. Aliquot and freeze at -20°C.

Molecular Information

CAS Number: 946870-92-4
Molecular Weight: 9,111 g/mol
Formula: C₄₀₀H₆₂₅N₁₀₉O₁₂₁S
Quality & Testing

Each batch is tested and documented to support research transparency and consistent research workflows. Certificates of Analysis (COAs) are provided by batch so researchers can reference the specific analytical results tied to the exact lot associated with their order. This supports clearer recordkeeping, improved comparability across experiments, and stronger traceability over time.
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Quality documentation is designed to help researchers confirm key batch attributes before use, including identity verification and purity results using established analytical methods such as HPLC and mass spectrometry where applicable. COAs typically include the batch identifier, test methods performed, and reported results, allowing researchers to maintain complete lab records and improve reproducibility across protocols and study timelines.

Batch Transparency

Every unit is associated with a batch identifier to support traceability and reproducible research. Batch tracking helps researchers link their materials to the exact analytical documentation for that production lot, which is important when comparing results across different runs, timelines, or study conditions. This also makes it easier to maintain clean lab records and verify continuity when repeating protocols.
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Certificates of Analysis (COAs) are organized by batch so you can reference the specific results tied to the batch you received. To use this system, locate the batch number on the vial label or packaging and match it to the corresponding COA for that SKU. Save the COA and batch number alongside your research notes so your documentation stays complete and auditable over time.

Specifications
Property
Value
Product Name
IGF-1 LR3
Catalog / SKU
IGF-1 LR3 – 1 mg
Form
Lyophilized powder
Net Quantity
1 MG PER VIAL
Purity (HPLC)
(View COA Page)
Intended Use
Laboratory research use only.

Every Batch Verified.

HPLC Analysis

High-Performance Liquid Chromatography confirms peptide purity and identity.

Mass Spectrometry

Molecular weight verification through advanced mass spec analysis.

Endotoxin Testing

LAL assay confirms endotoxin levels meet strict specifications.

Research Use Compliance

All products on this site are for research and development use only. Products are not for human consumption of any kind. The statements made on this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease.

Native Peptides is a chemical supplier. Native Peptides is not a compounding pharmacy or chemical compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act. Native Peptides is not an outsourcing facility as defined under Section 503B of the Federal Food, Drug, and Cosmetic Act.

All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.

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Native Peptides products are intended exclusively for laboratory research and in-vitro research purposes only. They are not intended for human or veterinary use.

You acknowledge that you understand and accept full responsibility for complying with all applicable local, state, and federal laws and regulations regarding the handling and use of research materials.